Epinephrin Content of Adrenals
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چکیده
In a study, mainly in cats, of the epinephrin discharge caused by electrical stimulation of the splanchnic nerves' we were led to consider the question whether the amount of epinephrin liberated by a given strength and duration of stimulation is related to the store of epinephrin already present in the adrenals, or is independent of that store. Desiring to compare the amount liberated in animals whose content was presumably high with the amount liberated in animals whose content was presumably low, we tried to exhaust the store, as far as possible, before the experiment on the liberation was made, by some of the procedures which according to Elliott2 cause diminution of the epinephrin load. Morphine was tried and also -tetrahydronaphthylamine, since Elliott states that these drugs produce marked exhaustion. But as in cats they also cause wide dilatation of the pupil, and we were using the eye reactions as one of the criteria of the presence of epinephrin in the blood, we eventually had recourse to frightening the cat by a dog. Elliott attributes the loss of epinephrin from the glands, induced by morphine and -tetrahydronaphthylamine, to the fright occasioned in cats by these substances. But he did not make any experiments on the effect of actual fright, although he says that "the most direct
منابع مشابه
The Influence of Certain Factors, Especially Emotional Disturbances, on the Epinephrin Content of the Adrenals
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تاریخ انتشار 2004